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Neuropeptide
PE-22-28
Synthetic peptide derived from spadin studied in neurological research.
$70.00
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Don't forget your reconstitution solution
Bacteriostatic Water 30mL
$25.00
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Lab Verified
HPLC-MS + endotoxin
Same-Day Ship
Orders by 2PM EST
Damage Coverage
Free replacement
Discreet Packaging
Plain outer box
Research Use Only
Not for human or veterinary consumption. For laboratory and in-vitro research purposes only.
Description
PE-22-28 is a synthetic peptide derived from spadin for research on TREK-1 channel studies.
Reconstitution
Reconstitute with bacteriostatic water in your preferred ratio. Store reconstituted vials refrigerated (2–8 °C) and use within recommended timeframes for your protocol.
Storage
Unreconstituted lyophilized powder stable at room temperature for short periods; refrigerate (2–8 °C) for long-term storage. Avoid repeat freeze/thaw cycles.
- Dose
- 5mg
- Purity
- ≥ 99%
- Form
- Lyophilized powder
- Storage
- Refrigerate after reconstitution
- Origin
- USA — synthesized & shipped domestically
- Testing
- HPLC-MS, MALDI, endotoxin screen
Certificate of analysis available on request
The batch certificate for this item isn't published online yet. Request it here and we'll email you the lab report for the batch you receive.
Research Overview
PE-22-28 is a synthetic 7-amino-acid peptide derived from the spadin sequence. It is studied as a TREK-1 potassium-channel blocker in neurological research models.
Mechanism of Action
Selectively blocks TREK-1 (KCNK2) two-pore-domain potassium channels in research models, with downstream effects on neuronal excitability.
Research Applications
- TREK-1 channel pharmacology
- Neuronal excitability research
- Spadin-pathway studies
Reconstitution & Handling
Certificate of Analysis
Lot / Batch
QP-2025-6285
- Product
- PE-22-28
- Manufacture date
- 2025-06-22
- Test date
- 2025-06-25
- Expiration
- 2028-06-22
- Appearance
- White to off-white lyophilized powder
- Identity
- Confirmed — matches reference standard
- Purity (HPLC)
- 99.90%
- Water content (KF)
- 1.70%
- Endotoxin (LAL)
- < 0.05 EU/mg
- Bioburden
- < 1 CFU / vial
- Analytical methods
- RP-HPLC, ESI-MS, MALDI-TOF, LAL endotoxin assay
- Released by
- QPUSA Quality Assurance Lab
