Sequence & Structure
L-Glutathione Sequence, Molecular Weight & Chemical Identity
3 min read•Published 2025-05-17•Quality Peptide USA Research
L-Glutathione (reduced form, GSH) is a naturally occurring tripeptide composed of glutamate, cysteine, and glycine. It is the most abundant intracellular antioxidant in mammalian cells and is widely used in oxidative-stress, detoxification, and redox-biology research.. This guide covers sequence & structure for L-Glutathione — written for laboratory researchers sourcing US-synthesized peptides from Quality Peptide USA.
Primary Sequence
The primary sequence of L-Glutathione is recorded as: γ-L-Glutamyl-L-cysteinyl-glycine. Sequence integrity is verified during release testing using analytical reverse-phase HPLC compared against a reference standard, with mass spectrometry confirming the expected molecular ion.
Molecular Formula and Weight
L-Glutathione carries the molecular formula C10H17N3O6S and a calculated monoisotopic weight of approximately ≈ 307.32 g/mol. These values are essential for accurate molar-concentration calculations during reconstitution and for normalizing dose curves across studies.
Identifiers and Synonyms
CAS Registry: 70-18-8. L-Glutathione is also referenced in the literature under its full chemical name and developmental designations. When searching publications, querying both the common and chemical names typically surfaces the broadest body of work.
Structural Notes for Researchers
L-Glutathione is supplied as a lyophilized solid with a white to off-white appearance. Researchers should reconstitute in sterile bacteriostatic water unless their assay calls for a specific buffer (e.g., 0.1% acetic acid for hydrophobic peptides). Quality Peptide USA publishes the full chemical-identity card on every product page so that incoming-QC checks can be performed against a known reference.
Research Use Only
All content is for laboratory and in-vitro research contexts only. Not intended to diagnose, treat, or prevent any condition. Not for human or veterinary consumption.
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