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Storage & Stability

L-Glutathione Storage & Stability: Cold Chain, Half-Life & Shelf Life

3 min readPublished 2025-07-19Quality Peptide USA Research

L-Glutathione (reduced form, GSH) is a naturally occurring tripeptide composed of glutamate, cysteine, and glycine. It is the most abundant intracellular antioxidant in mammalian cells and is widely used in oxidative-stress, detoxification, and redox-biology research.. This guide covers storage & stability for L-Glutathione — written for laboratory researchers sourcing US-synthesized peptides from Quality Peptide USA.

Lyophilized Shelf Life

Sealed lyophilized L-Glutathione stored at 2–8°C maintains potency through the expiration date listed on the certificate of analysis (typically 24–36 months from manufacture). Short transit exposure to room temperature during shipping does not meaningfully degrade lyophilized peptide — the vacuum-sealed solid form is highly stable. Once received, refrigerate promptly for long-term storage.

Reconstituted Solution Stability

Lyophilized: 2–8°C, protect from light. Reconstituted: refrigerate, use within 14 days. Benzyl alcohol in bacteriostatic water provides bacteriostatic protection but does not extend chemical stability indefinitely. Investigators running multi-week protocols should plan their aliquoting strategy in advance.

Reported Research Half-Life

Reported in-vitro / preclinical half-life for L-Glutathione: Short systemic life (research models) Half-life depends on study system — plasma, tissue culture media, and intact-animal models all yield different effective windows.

Cold-Chain Shipping by Quality Peptide USA

Every order of L-Glutathione ships with insulated cold packaging for transit, dispatched from US facilities on the same day for orders placed before 2 PM EST. Tracking is provided on every shipment so research teams can plan receiving and cold-room storage.

Research Use Only

All content is for laboratory and in-vitro research contexts only. Not intended to diagnose, treat, or prevent any condition. Not for human or veterinary consumption.

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